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Rohitash Jamwal, PhD student

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Rohitash Jamwal, PhD student

Research interests
Impact of disease state on drug disposition enzymes and transporters, High-throughput Proteomics, Herb/drug-drug interactions.

Current research

  • Quantification of drug disposition enzymes and transporters in human liver using mass spectrometry
  • Effect of diabetes and NAFLD on drug disposition enzymes and transporters in human liver 
  • Quantification of major cannabinoids and their metabolites in human plasma 

Previous research
Herb-drug interactions, Herbal drug discovery for treatment of erectile dysfunction (ED), Herbal pharmacokinetics

Professional experiences
Summer Intern, Proteomics, Amyris Inc., Emeryville, CA, May – Aug 2017

Research Officer, Natural Remedies Pvt. Ltd, India, 2009-14

Senior Research Fellow, Indian Council of Medical Research, India, 2012-14

Education
PhD, Pharmacokinetics, University of Rhode Island, Kingston, RI, 2014-Present
MS, Biotechnology, Amity University, India, 2007-09
BS Biotechnology Jaypee Institute of Information Technology, India, 2003-07

Contact details
Office: 495I, Lab: 490
Email: rohitash@uri.edu, rohitash@my.uri.edu
Mailing Address: 7 Greenhouse Road, Kingston, RI 02881

ORCID ID: 0000-0002-3747-3894

Publications

  • Jamwal R, Barlock BJ, Adusumalli S, Ogasawara K, Simons BL, Akhlaghi F. Multiplex and Label-Free Relative Quantification Approach for Studying Protein Abundance of Drug Metabolizing Enzymes in Human Liver Microsomes Using SWATH-MS. Journal of Proteome Research, 2017 [Epub ahead of print]
  • Jamwal R, Topletz AR, Ramratnam B, Akhlaghi F. Ultra-high performance liquid chromatography tandem mass spectrometry for simple and simultaneous quantification of cannabinoids. Journal of Chromatography B, 2017, 1048, 10-18
  • Shukla A, Jamwal R, Bala K. Adverse effect of combined oral contraceptive pills. Asian Journal of Pharmaceutical and Clinical Research, 2017, 10(1):17-21
  • Goswami SK, Inamdar MN, Dethe S, Gururaj GM, Jamwal R, Deepak M, Agarwal A. Erectogenic and aphrodisiac property of Moringa oleifera: Involvement of soluble epoxide hydrolase enzyme. Phytotherapy Research, 2016, 30(7):1119-27
  • Goswami SK, Gangadarappa SK, Vishwanath M, Razdan R, Jamwal R, Bhadri N, Inamdar MN. Antioxidant potential and ability of phloroglucinol to decrease formation of advanced glycation end products increase efficacy of sildenafil in diabetes-induced sexual dysfunction of rats. Sexual Medicine, 2016, 4(2):e104-12
  • Jamwal R, Goswami SK. Gut microbiota and its role in metabolism of common drugs–a short review. Pharmacology, Toxicology and Biomedical Reports, 2015, 1(3): 98-103
  • Goswami SK, Inamdar MN, Jamwal R, Dethe S. Effect of Cinnamomum cassia Blume. methanol extract on arginase and sexual function of young male Wistar rats. Journal of Sexual Medicine, 2014, 11(6):1475-83
  • Goswami SK, Inamdar MN, Jamwal R, Dethe S. Cinnamomum cassia Blume. extract increased sexual function in aged rat. Journal of Young Pharmacists, 2013; 5(4): 148–153
  • Goswami SK, Inamdar MN, Pandre MK, Jamwal R, Dethe S. Erectogenic and aphrodisiac effects of Butea frondosa in rats: Involvement of enzyme inhibition. Evidence-Based Complementary and Alternative Medicine, Aug 2013
  • Goswami SK, Pandre MK, Jamwal R, Dethe S, Agarwal A, Inamdar MN. Screening of Rho kinase 2 inhibitory activity of Indian medicinal plants for management of erectile dysfunction. Journal of Ethnopharmacology, 2012, 144(3): 483-9
  • Mehrotra S, Jamwal R, Shyam R, Meena DK, Mishra K, Patra R, De R, Mukhopadhyay A, Srivastava AK, Nandi SP. Anti-Helicobacter pylori and antioxidant properties of Emblica officinalis pulp extract: A potential source for therapeutic use against gastric ulcer. Journal of Medicinal Plants Research, 2011, 5(12): 2577-83

Outside lab activities/hobbies
An avid endurance athlete, mad about cycling, basketball and loves running. Plays cricket and badminton at times.