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Armin Sadighi, PhD student

armin
Armin Sadighi, PhD student

About me
I have received my Bachelor’s degree in Cellular and Molecular Biology (microbiology) from University of Isfahan, Isfahan, Iran. I continued my academic studies in the field of “Medical Nanotechnology,” with emphasis in nanodrug delivery systems, biocatalysis, and nanobiocatalyst. In fall 2014, I joined Akhlaghi Lab for my PhD in Pharmaceutics and Pharmacokinetics. My major focus is drug-drug interaction and oral bioavailibity of levothyroxine and other related metabolites using Caco-2 monolayer cell culture as a well-known high throughput in vitro model.

Research interest
Pharmacokinetics and pharmacodynamics, drug metabolism, pharmaceutics, drug-drug interaction.

Current research
Thyroid oral absorption, leaky gut syndrome, drug-drug interaction and metabolism, drug formulation and delivery.

Previous research
Pharmaceutical nanotechnology, inorganic nanoparticles, biocatalyst, and nanobiocatalyst.

Education
BS, Cell and Molecular Biology. University of Isfahan, Iran, 2004-08
MS, Medical Nanotechnology, Tehran University of Medical Sciences, Iran, 2008-11
PhD, Pharmaceutics and Pharmacokinetics, University of Rhode Island, Kingston, USA, 2014-Present

Contact details
arminsadighi@my.uri.edu

Publications
Sadighi A., Faramarzi M.A., Congo red decolorization by immobilized laccase through chitosan nanoparticles on the glass beads. J Taiwan Inst Chem Eng 44 (2013) 156–162.
Faramarzi M.A., Sadighi A., Insights into biogenic and chemical production of inorganic nanomaterials and nanostructures. Adv Colloid Interface Sci 189–190 (2013) 1–20.
Ghasemi S., Sadighi A.,  Heidary M., Bozorgi-Koushalshahi M., Habibi Z., Faramarzi M. A., Immobilisation of lipase on the surface of magnetic nanoparticles and non-porous glass beads for regioselective acetylation of prednisolone. IET Nanobiotechnol 7 (2013) 100-108.
Sadighi A., Ostad S.N., Rezayat S.M., Foroutan M.,  Faramarzi M.A., Dorkoosh F.A. Mathematical modelling of the transport of hydroxypropyl-β-cyclodextrin inclusion complexes of ranitidine hydrochloride and furosemide loaded chitosan nanoparticles across a Caco-2 cell monolayer. Int J Pharm. 422 (2012) 479–488.
Forootanfar H., Movahednia M.M., Yaghmaei S., Tabatabaei-Sameni M., Rastegar H., Sadighi A., Faramarzi M.A., Removal of chlorophenolic derivatives by soil isolated ascomycete of Paraconiothyrium variabile and studying the role of its extracellular laccase. J Hazard Mater 209–210 (2012) 199–203.

Outside lab activities/hobbies
Most of my spare time in the evening or weekend is taken up with listening to light and traditional pop and classic music, watching film and reading books in the fields of literature, psychology, philosophy, and history. Team sports like badminton, volleyball, and football are a favorite past time of mine as they give me a chance to meet new people and make friends.